| Intended Use |
The Canine Distemper Virus Antigen Rapid Test (Secretions) is a lateral flow immunochromatographic assay for the qualitative detection of antigen of Canine Distemper Virus (CDV Ag) in secretions from dog's eyes, nasal cavities, and ocular or in serum, plasma specimen.
| What is the Canine distemper? |
Canine distemper is a highly contagious viral disease that affects dogs worldwide. It is caused by the canine distemper virus and is spread through contact with bodily fluids from infected dogs, such as saliva, urine, or blood.
The symptoms of canine distemper can vary depending on the severity of the infection. Common symptoms include runny nose, coughing, fever, lethargy, vomiting, diarrhea, and loss of appetite. More severe cases can lead to seizures, paralysis, and even death.

| Clinical Signs |
An infected dog with purulent nasal discharge and a hyperkeratotic nose.
Dogs can exhibit a wide range of CDV symptoms, including none at all, mild respiratory symptoms similar to kennel cough, severe pneumonia with vomiting, bloody diarrhea, and death.
Runny nose, vomiting, diarrhea, dehydration, excessive salivation, coughing and/or labored breathing, appetite loss, and weight loss are typical symptoms. If neurological signs develop, incontinence may ensue. A localized involuntary twitching of muscles or groups of muscles, seizures accompanied by salivation and jaw movements—commonly referred to as "chewing-gum fits" or, more accurately, "distemper myoclonus"—are central nervous system symptoms. As the illness worsens, the seizures become grand mal convulsions, which are followed by the animal's death.

| Principle |
Canine Distemper Virus Antigen Rapid Test is a qualitative lateral flow immunochromatographic assay for detection of antigens of Canine Distemper Virus (CDV). The device has a testing window. The testing window has T (test) region and C (control) region.
During testing, sample is applied into the sample well on the device card. CDV antigens, if present in specimen, react with the pre-coated anti-CDV antibodies in the test strip. The mixture then migrates upward on the membrane chromatographically by capillary action and reacts with anti-CDV antibodies on the membrane in the test line region. If the specimen contains Canine Distemper Virus, a colored line will appear in the test line region indicating a positive result. If the specimen does not contain CDV antigens, a colored line will not appear in the test line region indicating a negative result. To serve as a procedural control, a colored line will always appear in the control line region indicating that proper volume of specimen has been added and membrane wicking has occurred.
| Additional Special Equipment |
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Materials Provided |
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Droppers ·
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Swabs
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Plastic tubes with buffer
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Package insert
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Materials Required But Not Provided |
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Timer

| Direction For Use |
Allow the device, specimen, buffer, and/or controls to equilibrate to room temperature (15-30 °C) prior to testing.
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Remove the device from the foil pouch and use it as soon as possible. Best results will be obtained if the assay is performed within one hour.
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Collect dog's ocular and nasal secretions with the swab provided. Make the swab wet sufficiently. Note: Collect ocular secretion from upper and lower eyelids, please avoid secretions at the corner of the eye. Insert the wet swab into the provided plastic tubes with buffer. Agitate it to assure good sample extraction. If using serum or plasma specimen, use the dropper to collect the specimen. Place 3 drops of serum or plasma into the assay buffer tube for dilution. The diluted sample is used as sample extraction.
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Place the device on a clean and level surface. Hold the dropper vertically and transfer 3 drops of extracted sample (approximately 120 μl) to the specimen well (S) of the Canine Distemper Virus Antigen Rapid Test device, then start the timer. See illustration above.
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Read the result in 5-10 minutes. Do not interpret results after 10 minutes.

| Performance Characteristics |

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Relative Sensitivity: 97.96% (95%CI*: 89.15%-99.95%)
- Relative Specificity: 97.50% (95%CI*: 86.84%-99.94%)
- Accuracy: 97.75% (95%CI*: 92.12%-99.73%)
- *CI = confidence interval compared to RT-PCR method.
Why choose us?
- Our Chinese factory is committed to using only the best materials and manufacturing methods to produce our Rapid Test Diagnostics products.
- We take science and technology innovation as the source of power, and gather a group of excellent scientific research team.
- With years of experience in the industry, we have become a trusted source for Rapid Test Diagnostics products.
- With the technology innovation and constant commitment to our customers, we are confident to be your first choice of professional Canine Distemper Virus Antigen Rapid Test.
- Our Rapid Test Diagnostics products are backed by a comprehensive warranty and support program.
- Every employee of the company is an important link in the company's overall value chain.
- Our Rapid Test Diagnostics products are easy to read and interpret, saving healthcare professionals time and effort.
- Creating high quality Canine Distemper Virus Antigen Rapid Test and leading the industry forward as our corporate mission, which indicates the development direction of the enterprise, also cohesion of the enterprise's social responsibility.
- We strive to exceed our clients' expectations when it comes to the quality and performance of our Rapid Test Diagnostics products.
- Adhering to the principle of credibility first, we always fulfill our promise and establish good reputation both inside and outside the company.
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