| Product Introduction: |
The Canine Parainfluenza Virus Antigen Test Cassette is a rapid chromatographic immunoassay for qualitative detection of CPIV antigen in nasopharyngeal swab specimens. It is intended to aid in the rapid differential diagnosis of CPIV infections.
| Components: |
| Composition |
 |
| Materials Provided | Test devices |
| Plastic tubes with buffer | |
| Droppers | |
| Swabs | |
| Package insert | |
| Materials Required but Not provided | Timer |
| Conditions and scope of use |
|
The test kit can be stored at room temperature or refrigerated (4-30°C) for the duration of the shelf life. The test must remain in the sealed pouch until use. DO NOT FREEZE. Does not use beyond the expiration date.
| SPECIMEN COLLECTION AND PREPARATION |
|
1.Use the sterile swab supplied in the Canine Parainfluenza Virus Antigen Test Cassette.
2.Insert this swab into the nostril that presents the most secretion under visual inspection.
3.Using gentle rotation, push the swab until resistance is met at the level of the turbinates (less than one inch in the nostril).
4.Rotate the swab three times against the nasopharyngeal wall.
5.It is recommended that swab specimens be processed as soon as possible after collection. If swabs are not processed immediately they should be placed into a dry, sterile, and tightly sealed plastic tube for storage. Swabs can be stored dry at room temperature for up to 24 hours
| Testing Procedure |
|
Bring the pouch to room temperature before opening it. Remove the test device from the sealed pouch and use it as soon as possible. Best results will be obtained if the assay is performed within one hour. Step of the testing：
1.Remove the test strip from the foil pouch and collect the specimen with swab.
2.Place the swab specimen in the dilution buffer tube and fully mixed.
3.Place the test device on a clean and level surface.
4.Hold the dropper vertically and transfer 3 full drops of buffer specimen (approx. 120l) to the specimen well (S) of the test device, and then start the timer. Read the result in 10 minutes. Avoid trapping air bubbles.
| Canine Parainfluenza Virus Antigen Test Cassette Interpretation of Results |
|
| Positive: | One red line appears in the control region (C). No apparent red or pink line appears in the test region (T). |  |
| Negative: | Two distinct red lines appear. One line should be in the control region (C) and another line should be in the test region (T). |  |
| Invalid: | Control line fails to appear. Insufficient specimen volume or incorrect procedural techniques are the most likely reasons for control line failure. Review the procedure and repeat the test with a new test device. If the problem persists, discontinue using the test kit immediately and contact your local distributor. |  |
| What is the Canine Parainfluenza Virus: |
Canine parainfluenza virus (CPIV) causes acute infectious respiratory illness in dogs worldwide (kennel cough). It replicates in upper respiratory epithelial cells, frequently causing no symptoms or rather moderate respiratory disease. Co-infections with other organisms, such as B. bronchiseptica, may worsen respiratory illness (Buonavoglia & Martella, 2007). CPIV is typically transmitted by aerosols, although it can also be transferred through direct and indirect contact with contaminated fluids. Parainfluenza viruses aerosolized have been demonstrated to be infectious for 4-12 days on a nonporous, plastic surface at 18-20°C (Parkinson et al., 1983).
The virus is made up of a single stranded RNA genome with negative polarity that is enveloped by a lipid envelope derived from host cells. CPIV's outer membrane contains both hemagglutinin and neuraminidase activity (HN attachment glycoprotein). The nucleoprotein (NP), V/phosphoprotein (V/P), matrix (M), fusion (F), small hydrophobic (SH), hemagglutinin-neuraminidase (HN), and large (L) genes are all included in the viral genome. The HN protein is involved in viral infection through cell attachment and causes hemagglutination. HN also possesses neuraminidase activity. The F protein is responsible for the viral envelope fusing with the cell membrane. The V protein reduces IFN production and inhibits IFN signaling.The V protein reduces IFN production and inhibits IFN signaling. The virus's interaction with the IFN system is recognized as a significant aspect in the infection's outcome.
Why choose us?
- Our Rapid Test Diagnostics products are backed by a comprehensive warranty and support program.
- 'Quality first, technology first, honesty and trustworthiness' has always been our business tenet.
- Our Chinese factory is committed to providing our clients with the highest quality Rapid Test Diagnostics products at affordable prices.
- The company is committed to highlighting product quality, value and service characteristics, so that the good relationship we have established with our customers can be sustained.
- Our Rapid Test Diagnostics products are designed to be accurate, reliable, and easy to use.
- Our company will build a high-tech talent highland, improve the ability of technological innovation, and establish a good brand image.
- We have a dedicated quality control team to ensure that all of our Rapid Test Diagnostics products meet our strict standards.
- We always adhere to the high degree of unity of economic and social responsibilities and show a good corporate image.
- Our Rapid Test Diagnostics products are manufactured in compliance with the highest industry standards for quality and safety.
- The production cycle of the Canine Parainfluenza Virus Antigen Test Cassette is short. As long as you place an order, we will process and transport the goods to you in the shortest time.
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